Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.34 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.33 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31245581 | 0.98 | NQO2 (0.36) | NQO2KDM4ECYP19A1MCHR1YTHDF2 | |
| SCHEMBL11830593 | 0.73 | RXFP1 (0.44) | NQO2KDM4ECYP19A1 | |
| Hydrochloric Acid SCHEMBL31245595 | 0.69 | NQO2 (0.33) | NQO2KDM4ECYP19A1YTHDF2 | |
| Hydrochloric Acid SCHEMBL31245622 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL31245617 | 0.66 | NQO2 (0.33) | NQO2KDM4ECYP19A1YTHDF2 | |
| SCHEMBL27404791 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL31245596 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL31245597 | 0.64 | — | — | |
| SCHEMBL9919110 | 0.64 | ADORA3 (0.42) | KDM4EMCHR1 | |
| Hydrochloric Acid SCHEMBL31233821 | 0.64 | BRPF1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130064-A1 | SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Karuna Therapeutics, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024130066-A1 | SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | Karuna Therapeutics, Inc. (US) | 2024-06-20 | — | — | WO | disclosed |