Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31485690 | 0.81 | DHODH (0.44) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL3279571 | 0.79 | MEN1 (1.00) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL5771649 | 0.73 | MAPK10 (0.70) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL2501726 | 0.73 | KMT2A (0.70) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL29391624 | 0.72 | KMT2A (0.76) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL221242 | 0.72 | KMT2A (0.76) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL30167997 | 0.72 | MEN1 (0.76) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL3265731 | 0.72 | MEN1 (0.76) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL29274138 | 0.71 | MEN1 (0.56) | MEN1KMT2AMAPK10GFERNPC1 | |
| SCHEMBL31220877 | 0.71 | MAPK10 (0.73) | MEN1KMT2AMAPK10GFERNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043344-C | New heterocyclic compounds | KRONSEDER MASCHF KRONES (JP) | 1999-05-12 | — | — | CN | claimed |