Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | GFER | P55789 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CCNK | O75909 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145899 | 0.83 | KMT2A (0.43) | MAPK10MEN1KMT2AGFERNPC1 | |
| SCHEMBL3279571 | 0.83 | MEN1 (1.00) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL31220877 | 0.82 | MAPK10 (0.73) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL7941542 | 0.82 | MAPK10 (0.73) | MAPK10MEN1KMT2AGFERKDR | |
| SCHEMBL30855342 | 0.81 | KMT2A (0.41) | MAPK10MEN1KMT2AGFERNPC1 | |
| SCHEMBL15227141 | 0.81 | KMT2A (0.41) | MAPK10MEN1KMT2AGFERNPC1 | |
| SCHEMBL4143510 | 0.81 | KMT2A (0.41) | MAPK10MEN1KMT2AGFERNPC1 | |
| SCHEMBL8263591 | 0.78 | GAA (0.47) | MAPK10MEN1KMT2AGFERNPC1 | |
| SCHEMBL28734979 | 0.78 | MAPK10 (0.51) | MAPK10MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3265735 | 0.78 | MEN1 (0.80) | MAPK10MEN1KMT2AGFERKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293503-A1 | Polyaminopyridines and method for producing same | SUMITOMO SEIKA CHEMICALS CO., LTD (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |