Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28344709 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA2CA4 | |
| Pyridine SCHEMBL273314 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA2CA4 | |
| Pyridine SCHEMBL28548371 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA2CA4 | |
| Pyridine SCHEMBL28901683 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA2CA4 | |
| Pyridine SCHEMBL26605130 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA2CA4 | |
| Benzene SCHEMBL2367770 | 1.00 | NAPRT (0.60) | NAPRTTSHRTDP1CA2CA4 | |
| Pyridine SCHEMBL15647489 | 0.97 | TSHR (0.56) | NAPRTTSHRTDP1CA2CA4 | |
| Pyridine SCHEMBL28958471 | 0.97 | TSHR (0.56) | NAPRTTSHRTDP1CA2CA4 | |
| Pyridine SCHEMBL1652035 | 0.97 | TSHR (0.56) | NAPRTTSHRTDP1CA2CA4 | |
| Pyridine SCHEMBL27510816 | 0.97 | TSHR (0.56) | NAPRTTSHRTDP1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113543706-B | Electrode comprising a conductive acrylate-based pressure sensitive adhesive | 汉高股份有限及两合公司 | 2024-07-23 | — | — | CN | claimed |
| CN-118235027-A | Ion conductive composition for thermal sensor | 汉高股份有限及两合公司 | 2024-06-21 | — | — | CN | claimed |
| CN-117185566-A | Treatment method and treatment system for wastewater generated in process of extracting phenolic compounds from coal tar | 陕西煤业化工集团神木天元化工有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116535311-A | Novel synthesis method of Carbonic acid | 风火轮(上海)生物科技有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-115989294-A | Dry stimulating electrode | 汉高股份有限及两合公司 | 2023-04-18 | — | — | CN | claimed |
| CN-113557281-A | Dry electrode binder | 汉高股份有限及两合公司 | 2021-10-26 | — | — | CN | claimed |
| CN-113543706-A | Electrode comprising a conductive acrylate-based pressure sensitive adhesive | 汉高股份有限及两合公司 | 2021-10-22 | — | — | CN | claimed |
| CN-108752285-A | A kind of synthetic method of Valsartan | 浙江华海药业股份有限公司 | 2018-11-06 | — | — | CN | claimed |
| CN-102531915-B | Method for preparing ethylene diamine through condensation and ammoniation by using bronsted acid ion liquid to catalyze ethanolamine | HUAIBEI KEDA CHEMICAL CO LTD | 2013-08-07 | — | — | CN | claimed |
| CN-102531915-A | Method for preparing ethylene diamine through condensation and ammoniation by using bronsted acid ion liquid to catalyze ethanolamine | HUAIBEI KEDA CHEMICAL CO LTD | 2012-07-04 | — | — | CN | claimed |
| CN-1203073-C | Fused imidazopyridine derivatives, process for producing the same and crystalline forms | SHIONOGI & CO (JP) | 2005-05-25 | — | — | CN | claimed |
| CN-1419557-A | Novel process for producing fused imidazopridine derivative and novel crystal form | SHIONOGI & CO (JP) | 2003-05-21 | — | — | CN | claimed |
| JP-9117296-A | — | — | None | — | — | JP | disclosed |
| EP-4553061-A1 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-05-14 | — | — | EP | disclosed |
| CN-119546584-A | Bicyclic compounds and their use as pest control agents | PI工业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119403778-A | Process for producing fluorinated organic compound | 大金工业株式会社 | 2025-02-07 | — | — | CN | disclosed |
| US-4172832-A | Mercaptoalcohols and process for their manufacture | CIBA-GEIGY CORPORATION (US) | 1979-10-30 | — | — | US | disclosed |
| US-4122258-A | Process for producing desacetoxycephalosporin derivatives by heating a penicillin-1-oxide in presence of an organic sulfide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-10-24 | — | — | US | disclosed |
| US-3975385-A | 7-Trichloroacetamido-3-desacetoxy-cephalosporanic acid esters | RHONE-POULENC S.A. (FR) | 1976-08-17 | — | — | US | disclosed |
| US-3950427-A | ANTIINFLAMMATORY, ANTIPYRETIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |