Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.70 |
| ▸ | NPC1 | O15118 | 11/20 | 0.70 |
| ▸ | MAPT | P10636 | 10/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.70 |
| ▸ | TP53 | P04637 | 5/20 | 0.70 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.70 |
| ▸ | RELA | Q04206 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251987 | 0.90 | RAB9A (0.85) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL2354022 | 0.82 | RAB9A (1.00) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL12193319 | 0.81 | MCHR1 (0.55) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL4252909 | 0.78 | HDAC8 (0.76) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL8769840 | 0.78 | RAB9A (0.78) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL8770201 | 0.78 | RAB9A (0.78) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL1535782 | 0.77 | NPC1 (0.69) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL5084566 | 0.77 | USP2 (0.66) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL30828596 | 0.77 | RAB9A (0.78) | RAB9ANPC1MAPTSMN1; SMN2TP53 | |
| SCHEMBL8769429 | 0.77 | RAB9A (0.78) | RAB9ANPC1MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088805-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2012-01-03 | — | — | US | disclosed |
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | METHYLGENE INC. (CA) | 2007-09-13 | — | — | US | disclosed |
| US-7253204-B2 | Antiproliferative agents | METHYLGENE INC. (CA) | 2007-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213330-A1 | Anticancer agents; antiproliferative agents | HDAC1, HDAC11, HDAC5 | RAB9A 3036/4885NPC1 1293/4885MAPT 3612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.