Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CD74 | P04233 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27331830 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9AKDM4ECSF1RMAPT | |
| SCHEMBL27331824 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL27331694 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AKDM4ECSF1RMAPT | |
| SCHEMBL28298660 | 0.80 | BRD4 (0.63) | SMN1; SMN2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL28434856 | 0.75 | CYP19A1 (0.44) | RAB9AMEN1KMT2ABRD4MET | |
| SCHEMBL27331834 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2RAB9AKDM4ECSF1RMAPT | |
| SCHEMBL12427200 | 0.72 | MEN1 (0.55) | RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL26098876 | 0.71 | PTGS2 (0.49) | SMN1; SMN2RAB9AKDM4EMAPTNPC1 | |
| SCHEMBL17201431 | 0.71 | CYP1A2 (0.55) | SMN1; SMN2RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL27331802 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235384-A1 | COMPOUNDS FOR ENHANCING READ THROUGH OF GENES CONTAINING PREMATURE TERMINATION CODONS AND METHODS FOR MAKING AND USING THE SAME | SANOFI US SERVICES INC. (US) | 2023-12-07 | — | — | WO | disclosed |