Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12427200 | 0.82 | MEN1 (0.55) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL1629487 | 0.79 | BRD4 (0.39) | NPC1RAB9AMETBRD4QPCT | |
| SCHEMBL28298660 | 0.78 | BRD4 (0.63) | CYP19A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27331696 | 0.75 | SMN1; SMN2 (0.49) | CYP19A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL22276766 | 0.74 | SCN4A (0.46) | MEN1KMT2ANPC1RAB9ABRD4 | |
| SCHEMBL26354513 | 0.73 | PTGS2 (0.38) | MEN1KMT2ANPC1RAB9AMET | |
| SCHEMBL197283 | 0.73 | FYN (0.45) | CYP19A1 | |
| SCHEMBL9143504 | 0.72 | KDR (0.50) | MEN1KMT2ANPC1RAB9ASRC | |
| SCHEMBL22185240 | 0.71 | NPC1 (0.46) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL31530422 | 0.71 | BRD4 (0.43) | MEN1KMT2ANPC1RAB9ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654606-B | Triazole compound as well as preparation method and application thereof | 武汉朗来科技发展有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-112654606-A | Triazole compound and preparation method and application thereof | 武汉朗来科技发展有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-111434653-A | Triazole compound and preparation method and application thereof | 武汉朗来科技发展有限公司 | 2020-07-21 | — | — | CN | disclosed |