Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184810 | 0.88 | CA12 (0.43) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL8849171 | 0.82 | MMP8 (0.43) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL12920265 | 0.79 | ESR1 (0.52) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL5321055 | 0.78 | CA12 (0.47) | CA12CA1CA2CA9POLB | |
| SCHEMBL6905840 | 0.77 | MEN1 (0.46) | KMT2AGAAALDH1A1 | |
| SCHEMBL185043 | 0.77 | RAB9A (0.41) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL324361 | 0.76 | KMT2A (0.47) | KMT2AGAANPSR1ALDH1A1HPGD | |
| SCHEMBL13191486 | 0.74 | MMP8 (0.38) | CA12CA1CA2CA9KMT2A | |
| SCHEMBL1676908 | 0.74 | MAPT (0.46) | KMT2AGAANPSR1ALDH1A1HPGD | |
| SCHEMBL185201 | 0.74 | RAB9A (0.61) | GAANPSR1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402327-A1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | Advinus Therapeutics Private Limited (IN) | 2012-01-04 | — | — | EP | disclosed |