Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28111514 | 0.82 | NPSR1 (0.46) | NPSR1ALDH1A1TSHRGLARAB9A | |
| SCHEMBL27467328 | 0.81 | ALDH1A1 (0.54) | NPSR1ALDH1A1TSHRGLARAB9A | |
| SCHEMBL28624955 | 0.81 | CES2 (0.43) | NPSR1ALOX5ALDH1A1TSHRRAB9A | |
| SCHEMBL27757235 | 0.79 | APP (0.36) | — | |
| SCHEMBL28041937 | 0.79 | — | — | |
| Methyl Alcohol SCHEMBL28147253 | 0.73 | NPSR1 (0.58) | NPSR1ALOX5ALDH1A1TSHRGLA | |
| SCHEMBL1630634 | 0.73 | KMT2A (0.50) | NPSR1ALOX5RAB9APOLBL3MBTL1 | |
| SCHEMBL966681 | 0.73 | KMT2A (0.50) | NPSR1ALOX5RAB9APOLBL3MBTL1 | |
| SCHEMBL28864795 | 0.72 | NPSR1 (0.37) | NPSR1ALDH1A1TSHRGLARAB9A | |
| SCHEMBL75885 | 0.72 | NPSR1 (0.64) | NPSR1ALOX5ALDH1A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943234-A | Preparation method of sulfonylphenylurea herbicide safener | 常州大学 | 2022-01-18 | — | — | CN | claimed |
| CN-110372545-A | A kind of preparation method of the gliclazide intermediate tolylsulfonylurea of high-purity | 山东海佑福瑞达制药有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-113474388-B | Method for converting phenyl isocyanate | 陶氏环球技术有限责任公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-113943234-A | Preparation method of sulfonylphenylurea herbicide safener | 常州大学 | 2022-01-18 | — | — | CN | disclosed |
| CN-113943234-A | Preparation method of sulfonylphenylurea herbicide safener | 常州大学 | 2022-01-18 | — | — | CN | disclosed |
| CN-112239429-A | Discovery and application of novel structure and novel function of sulfonylurea herbicides with controllable soil degradation speed | 南开大学 | 2021-01-19 | — | — | CN | disclosed |
| CN-106588746-B | The preparation method of gliclazide side chain and the preparation method of gliclazide | 盘锦格林凯默科技有限公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-107790446-A | A kind of tolylsulfonylurea reaction tower cleaning device | 响水台舍化工有限公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-106588746-A | Preparation method of gliclazide side chain and preparation method of gliclazide | 盘锦格林凯默科技有限公司 | 2017-04-26 | — | — | CN | disclosed |
| CN-105439970-A | Discovery and application of sulfonylurea novel structure with controllable soil degradation speed | UNIV NANKAI | 2016-03-30 | — | — | CN | disclosed |
| CN-1043402-C | Herbicide tablets or capsules for paddy field application by throwing them into water | ISHIHARA SANGYO KAISHA (JP) | 1999-05-19 | — | — | CN | disclosed |
| CN-1049951-A | The weeding tablet or the capsule of paddy field application by throwing them | ISHIHARA SANGYO KAISHA (JP) | 1991-03-20 | — | — | CN | disclosed |