SCHEMBL27334288

SCHEMBL27334288

COC(=O)CCC(C(=O)OC)N(CCN)OC(=O)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPOR P19235 3/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.37
AKT1 P31749 1/20 0.37
ESRRB O95718 1/20 0.36
LMNA P02545 1/20 0.34
ALDH1A1 P00352 1/20 0.34
SLC1A1 P43005 1/20 0.34
ADRB2 P07550 2/20 0.34
ADRB1 P08588 2/20 0.34
ADRB3 P13945 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27330494 0.86 EPOR (0.41) EPORTSHRKMT2ASMN1; SMN2
SCHEMBL27330847 0.84 EPOR (0.44) EPORKMT2ALMNASMN1; SMN2
SCHEMBL27328769 0.83 ALDH1A1 (0.41) EPORTSHRKMT2ALMNAALDH1A1
SCHEMBL27328793 0.83 ALDH1A1 (0.41) EPORTSHRKMT2ALMNAALDH1A1
SCHEMBL27334285 0.81 CKS1B (0.39) KMT2ALMNAALDH1A1ADRB2ADRB1
SCHEMBL27331579 0.79 CA12 (0.42) EPORTSHRKMT2A
SCHEMBL27332527 0.75 MEN1 (0.46) TSHRKMT2ALMNASMN1; SMN2MAPT
SCHEMBL28533455 0.72 KMT2A (0.41) TSHRKMT2AAKT1ESRRBLMNA
SCHEMBL28533457 0.72 KMT2A (0.41) TSHRKMT2AAKT1ESRRBLMNA
SCHEMBL26179405 0.68 TSHR (0.46) TSHRKMT2ALMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024097355-A1 DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS VICINITAS THERAPEUTICS, INC. (US) 2024-05-10 WO disclosed