SCHEMBL27334285

SCHEMBL27334285

COC(=O)CCC(C(=O)OC)N(CCNC(=O)OC(C)(C)C)OC(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CKS1B P61024 1/20 0.39
SKP1 P63208 1/20 0.39
SKP2 Q13309 1/20 0.39
IDO1 P14902 1/20 0.39
SYK P43405 1/20 0.37
JAK3 P52333 1/20 0.36
BTK Q06187 1/20 0.36
MALT1 Q9UDY8 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
GAA P10253 1/20 0.36
CASR P41180 1/20 0.35
DRD2 P14416 2/20 0.34
SIGMAR1 Q99720 2/20 0.34
MAPT P10636 1/20 0.34
ALDH1A1 P00352 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TPSAB1 Q15661 1/20 0.34
TPSD1 Q9BZJ3 1/20 0.34
TPSG1 Q9NRR2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27330783 0.87 MMP1 (0.45) CKS1BSKP1SKP2IDO1SYK
SCHEMBL27328766 0.86 IDO1 (0.44) CKS1BSKP1SKP2IDO1SYK
SCHEMBL27331531 0.82 CTSS (0.43) CKS1BSKP1SKP2IDO1SYK
SCHEMBL27334288 0.81 EPOR (0.38) KMT2AGAAMAPTALDH1A1LMNA
SCHEMBL27332497 0.78 CTSL (0.49) GAAMAPTSMN1; SMN2
SCHEMBL30841405 0.78 SYK (0.45) CKS1BSKP1SKP2IDO1SYK
SCHEMBL14985158 0.74 DRD2 (0.40) CKS1BSKP1SKP2IDO1MEN1
SCHEMBL19698539 0.73 CKS1B (0.43) CKS1BSKP1SKP2IDO1SYK
SCHEMBL3047789 0.71 MEN1 (0.45) IDO1MALT1MEN1KMT2AGAA
SCHEMBL29720250 0.70 GPR88 (0.44) CKS1BSKP1SKP2IDO1SYK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024097355-A1 DEUBIQUITINASE-TARGETING CHIMERAS AND RELATED METHODS VICINITAS THERAPEUTICS, INC. (US) 2024-05-10 WO disclosed