Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 4/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.34 |
| ▸ | CDK2 | P24941 | 4/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952184 | 0.83 | SLC2A1 (0.41) | PNPPDPK1GDACDK1CCNB1 | |
| SCHEMBL6811648 | 0.81 | KDM5B (0.33) | KDM5B | |
| SCHEMBL17186408 | 0.79 | MGMT (0.40) | PNPHRH4PDPK1GDACDK1 | |
| SCHEMBL2385930 | 0.78 | ADORA2B (0.50) | PNPHRH4PDPK1GDACDK1 | |
| Hydrochloric Acid SCHEMBL18605989 | 0.78 | MGMT (0.40) | PNPHRH4PDPK1GDACDK1 | |
| SCHEMBL9806974 | 0.77 | PNP (0.44) | PNPHRH4PDPK1GDACDK1 | |
| SCHEMBL441798 | 0.76 | DPP4 (0.44) | PNPHRH4PDPK1GDACDK1 | |
| SCHEMBL6751932 | 0.76 | PNP (0.43) | PNPPDPK1GDACDK1CCNB1 | |
| SCHEMBL17186452 | 0.75 | OGA (0.45) | CDK2PIK3CGPIK3CAMTOR | |
| Hydrochloric Acid SCHEMBL18605857 | 0.74 | OGA (0.44) | CDK2PIK3CGPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048493-C | 06-substituted guanine derivatives, a process for their prepn. and their use | CANCER RES CAMPAIGN TECH (GB) | 2000-01-19 | — | — | CN | disclosed |
| CN-1145622-A | O 6Substituted guanine derivatives, process for their preparation and their use | CANCER RES CAMPAIGN TECH (GB) | 1997-03-19 | — | — | CN | disclosed |