Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27335385 | 0.81 | PNP (0.35) | KDM5B | |
| SCHEMBL17186400 | 0.79 | SIGMAR1 (0.35) | KDM5BALOX5 | |
| SCHEMBL5021599 | 0.78 | ADORA2B (0.43) | — | |
| Hydrochloric Acid SCHEMBL17186284 | 0.78 | SIGMAR1 (0.35) | KDM5BALOX5 | |
| SCHEMBL9806961 | 0.77 | ADORA2B (0.36) | — | |
| SCHEMBL441795 | 0.76 | ADORA2B (0.35) | — | |
| SCHEMBL6751928 | 0.76 | ADORA2B (0.35) | — | |
| SCHEMBL17186445 | 0.75 | OGA (0.45) | — | |
| Hydrochloric Acid SCHEMBL18605853 | 0.74 | OGA (0.44) | — | |
| SCHEMBL4964555 | 0.71 | PNP (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702683-B8 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER REC TECH LTD (GB) | 2004-09-08 | — | — | EP | disclosed |
| EP-0702683-A1 | 06-SUBSTITUTED GUANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING TUMOUR CELLS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |