Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.38 |
| ▸ | DUT | P33316 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | TEK | Q02763 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667111 | 0.83 | DUT (0.36) | DGAT1DUTEGFRIGF1RSRC | |
| SCHEMBL30902997 | 0.82 | DUT (0.35) | DGAT1DUTEGFRIGF1RSRC | |
| SCHEMBL30728198 | 0.79 | DUT (0.35) | DGAT1DUTEGFRIGF1RSRC | |
| SCHEMBL31319360 | 0.76 | NPC1 (0.32) | NPC1 | |
| SCHEMBL30903046 | 0.76 | DGAT1 (0.43) | DGAT1EGFRIGF1RSRCFLT4 | |
| SCHEMBL31319438 | 0.75 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL31319343 | 0.74 | PDE3B (0.32) | — | |
| SCHEMBL27041330 | 0.73 | DUT (0.37) | DGAT1DUTEGFRIGF1RSRC | |
| SCHEMBL6719621 | 0.72 | DGAT1 (0.42) | DGAT1DUTEGFRIGF1RSRC | |
| SCHEMBL30479870 | 0.72 | MAPT (0.42) | DGAT1DUTEGFRIGF1RSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105563-A1 | SUBSTITUTED BICYCLIC PYRIDONE DERIVATIVES | PFIZER INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024105563-A1 | SUBSTITUTED BICYCLIC PYRIDONE DERIVATIVES | PFIZER INC. (US) | 2024-05-23 | — | — | WO | disclosed |