SCHEMBL27337207

SCHEMBL27337207

c1ccc(-c2ccc(N(c3ccccc3-c3cc4c5ccccc5oc4c4ccccc34)c3cccc4ccccc34)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
GGPS1 O95749 1/20 0.34
ALDH1A1 P00352 4/20 0.32
MAPT P10636 4/20 0.32
KDM4E B2RXH2 3/20 0.32
HPGD P15428 3/20 0.32
HSD17B10 Q99714 3/20 0.32
TSHR P16473 2/20 0.32
ALOX15 P16050 1/20 0.32
CASP1 P29466 1/20 0.32
CASP7 P55210 1/20 0.32
AHR P35869 1/20 0.32
PRKDC P78527 3/20 0.32
PTGES2 Q9H7Z7 1/20 0.32
CYP1A1 P04798 3/20 0.32
CYP1A2 P05177 3/20 0.32
CYP1B1 Q16678 3/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
MAPK1 P28482 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27336959 1.00 ALOX5 (0.41) ALOX5GGPS1ALDH1A1MAPTKDM4E
SCHEMBL27337398 0.93 ALOX5 (0.41) ALOX5GGPS1ALDH1A1MAPTKDM4E
SCHEMBL27337208 0.93 ALOX5 (0.40) ALOX5GGPS1ALDH1A1MAPTKDM4E
SCHEMBL27337177 0.92 ALOX5 (0.40) ALOX5GGPS1ALDH1A1MAPTKDM4E
SCHEMBL23233344 0.92 ALOX5 (0.43) ALOX5GGPS1ALDH1A1MAPTKDM4E
SCHEMBL24888724 0.91 ALOX5 (0.41) ALOX5GGPS1ALDH1A1MAPTKDM4E
SCHEMBL24964213 0.91 ALOX5 (0.43) ALOX5GGPS1ALDH1A1MAPTKDM4E
SCHEMBL24471763 0.91 ALOX5 (0.40) ALOX5GGPS1ALDH1A1MAPTKDM4E
SCHEMBL10110097 0.91 ALOX5 (0.40) ALOX5GGPS1ALDH1A1MAPTKDM4E
SCHEMBL27336926 0.91 ALOX5 (0.43) ALOX5GGPS1MAPTHPGDAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023199832-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-10-19 WO disclosed