Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.59 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | PYGM | P11217 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30305564 | 0.84 | HRH4 (0.57) | HRH4DAOCDK1CCNB1CA12 | |
| SCHEMBL1144741 | 0.84 | HPGD (0.60) | HRH4DAOCDK1CCNB1CA12 | |
| SCHEMBL29063451 | 0.83 | HRH4 (0.56) | HRH4DAOCDK1CCNB1CA12 | |
| SCHEMBL30310556 | 0.83 | HRH4 (0.56) | HRH4DAOCDK1CCNB1CA12 | |
| SCHEMBL24740173 | 0.82 | HRH4 (0.56) | HRH4DAOCDK1CCNB1CA12 | |
| SCHEMBL16236158 | 0.82 | HRH4 (0.56) | HRH4DAOCDK1CCNB1CA12 | |
| SCHEMBL24896461 | 0.82 | HRH4 (0.56) | HRH4DAOCDK1CCNB1CA12 | |
| SCHEMBL23835756 | 0.82 | HRH4 (0.56) | HRH4DAOCDK1CCNB1CA12 | |
| SCHEMBL18354217 | 0.81 | NSD2 (0.61) | HRH4DAODRD2DRD3ALDH1A1 | |
| SCHEMBL10084620 | 0.79 | HRH4 (0.59) | HRH4DAOCA12CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245162-A2 | COMPOUNDS FOR TREATMENT A CORONAVIRUS INFECTION | TRAWSFYNYDD THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |