Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | PYGM | P11217 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144741 | 0.86 | HPGD (0.60) | HRH4DAOCA12CA9CDK1 | |
| SCHEMBL30310556 | 0.84 | HRH4 (0.56) | HRH4DAOCA12CA9CDK1 | |
| SCHEMBL27337665 | 0.84 | HRH4 (0.59) | HRH4DAOCA12CA9CDK1 | |
| SCHEMBL29063451 | 0.84 | HRH4 (0.56) | HRH4DAOCA12CA9CDK1 | |
| SCHEMBL24896461 | 0.80 | HRH4 (0.56) | HRH4DAOCA12CA9CDK1 | |
| SCHEMBL31392795 | 0.80 | KDM4E (0.58) | HRH4DAOCA12CA9CDK1 | |
| SCHEMBL6171590 | 0.80 | MEN1 (0.56) | HRH4DAOCA12CA9CDK1 | |
| SCHEMBL24740173 | 0.80 | HRH4 (0.56) | HRH4DAOCA12CA9CDK1 | |
| SCHEMBL16236158 | 0.80 | HRH4 (0.56) | HRH4DAOCA12CA9CDK1 | |
| SCHEMBL23835756 | 0.80 | HRH4 (0.56) | HRH4DAOCA12CA9CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023044509-A1 | PROCESS FOR MAKING CYSTEINE PROTEASE INHIBITORS AND COMPOUNDS PROVIDED BY THAT PROCESS | Pardes Biosciences, Inc. (US) | 2023-03-23 | — | — | WO | disclosed |