Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.41 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.36 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.36 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24681271 | 0.82 | NOTUM (0.53) | RORCNOTUMWDR91GPR119HDAC1 | |
| SCHEMBL29914409 | 0.82 | NOTUM (0.53) | RORCNOTUMWDR91GPR119HDAC1 | |
| SCHEMBL1394105 | 0.78 | CNR1 (0.49) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL27926423 | 0.77 | RORC (0.46) | RORCNOTUMGPR119AKR1C3ALK | |
| SCHEMBL31319987 | 0.72 | NOTUM (0.43) | RORCNOTUMALK | |
| SCHEMBL27330278 | 0.71 | KMT2A (0.51) | NOTUMMEN1KMT2ACA12CA1 | |
| SCHEMBL24681284 | 0.70 | RORC (0.41) | RORCGPR119ALKCA12CA1 | |
| SCHEMBL29914515 | 0.70 | RORC (0.41) | RORCGPR119ALKCA12CA1 | |
| SCHEMBL23960532 | 0.70 | RORC (0.47) | RORCUSP2NOTUMMEN1LMNA | |
| SCHEMBL24494992 | 0.69 | NPY5R (0.47) | RORCUSP2GPR119AKR1C3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1049888-C | Benzoylguanidine, process for preparing same, their use as medicine and medicine containing same | HOECHST AG (DE) | 2000-03-01 | — | — | CN | disclosed |
| CN-1050018-A | Benzoylguanidines, they the preparation method, they are as the application of medicament and the medicament that contains them | HOECHST AG (DE) | 1991-03-20 | — | — | CN | disclosed |