Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 4/20 | 0.45 |
| ▸ | PIM1 | P11309 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27274912 | 0.99 | EPHA2 (0.51) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL27271653 | 0.81 | LMNA (0.52) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9537382 | 0.81 | KMT2A (0.59) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL27323899 | 0.80 | LMNA (0.37) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9537740 | 0.80 | KMT2A (0.58) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL6211205 | 0.79 | LMNA (0.50) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9148377 | 0.78 | EPHA2 (0.57) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL11021112 | 0.78 | KMT2A (0.57) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL4902751 | 0.78 | LMNA (0.66) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL10904821 | 0.78 | LMNA (0.66) | EPHA2FLT4GSK3BRARBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1041155-A | Process for producing 1, 4-dihydro-4-oxo-1, 8-naphthyridine derivatives and salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 1990-04-11 | — | — | CN | claimed |
| CN-85103150-A | Process for producing antibacterial agent containing 1, 4-dihydro-4-oxo-1, 8-naphthyridine derivative and salt thereof | — | 1986-10-22 | — | — | CN | claimed |