Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27345669 | 0.82 | LMNA (0.46) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27344759 | 0.82 | PIM3 (0.35) | LMNAKMT2AMEN1RPS6KB1MATK | |
| SCHEMBL27335103 | 0.81 | TOP2A (0.48) | POLBKMT2AMEN1GSK3BRPS6KB1 | |
| SCHEMBL27338265 | 0.80 | EPHA2 (0.52) | LMNAKDM4EALDH1A1HTTPIM1 | |
| Hydrochloric Acid SCHEMBL27336325 | 0.80 | TOP2A (0.47) | POLBKMT2AMEN1GSK3BRPS6KB1 | |
| Hydrochloric Acid SCHEMBL27274912 | 0.80 | EPHA2 (0.51) | LMNAKDM4EALDH1A1HTTPIM1 | |
| SCHEMBL10440674 | 0.78 | PIM3 (0.61) | LMNAKDM4EALDH1A1HTTHPGD | |
| Hydrochloric Acid SCHEMBL10440710 | 0.77 | PIM3 (0.60) | LMNAKDM4EALDH1A1HTTHPGD | |
| SCHEMBL10440665 | 0.71 | LMNA (0.43) | LMNAKDM4EALDH1A1HTTPIM1 | |
| SCHEMBL8112233 | 0.69 | LMNA (0.51) | LMNAKDM4EALDH1A1HTTPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045972-A | 5-replaces-1,4-dihydro-4-oxo-naphthyridine-3-carboxylic acid (ester) antimicrobial drug | BRISTOL MYERS SQUIBB CO (US) | 1990-10-10 | — | — | CN | claimed |
| CN-1045972-A | 5-replaces-1,4-dihydro-4-oxo-naphthyridine-3-carboxylic acid (ester) antimicrobial drug | BRISTOL MYERS SQUIBB CO (US) | 1990-10-10 | — | — | CN | disclosed |