Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30343566 | 0.87 | MAPT (0.70) | ALDH1A1POLBTDP1MAPTMAPK1 | |
| SCHEMBL2226923 | 0.81 | ALDH1A1 (0.62) | ALDH1A1POLBTDP1MAPTMAPK1 | |
| SCHEMBL28570071 | 0.80 | ALDH1A1 (0.53) | ALDH1A1POLBTDP1MAPTMAPK1 | |
| SCHEMBL23507475 | 0.80 | ALDH1A1 (0.55) | ALDH1A1POLBTDP1MAPTMAPK1 | |
| SCHEMBL27339265 | 0.80 | TACR1 (0.53) | MAPTTACR1 | |
| SCHEMBL27339266 | 0.79 | KDM4E (0.60) | ALDH1A1TDP1MAPTTSHRKMT2A | |
| SCHEMBL27339267 | 0.79 | CCR5 (0.51) | POLBMAPTTSHRKMT2AMEN1 | |
| SCHEMBL5191004 | 0.78 | TSHR (0.63) | ALDH1A1POLBTDP1MAPTMAPK1 | |
| SCHEMBL9831262 | 0.76 | KDM4E (0.64) | ALDH1A1POLBTDP1MAPTMAPK1 | |
| SCHEMBL2562169 | 0.76 | RXFP1 (0.48) | ALDH1A1POLBMAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107434-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |