Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.60 |
| ▸ | WHR1 | P49842 | 2/20 | 0.57 |
| ▸ | EHMT2 | Q96KQ7 | 6/20 | 0.55 |
| ▸ | EHMT1 | Q9H9B1 | 6/20 | 0.55 |
| ▸ | STAT6 | P42226 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329878 | 0.92 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1KDM4EWHR1EHMT2 | |
| SCHEMBL13329880 | 0.92 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1KDM4EWHR1EHMT2 | |
| SCHEMBL22144613 | 0.86 | WHR1 (0.78) | SMN1; SMN2ALDH1A1PDE10AWHR1EHMT2 | |
| SCHEMBL22144610 | 0.86 | WHR1 (0.78) | SMN1; SMN2ALDH1A1PDE10AWHR1EHMT2 | |
| SCHEMBL20610678 | 0.85 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1KDM4EWHR1EHMT2 | |
| SCHEMBL2914245 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1KDM4EPDE10AWHR1 | |
| SCHEMBL20610675 | 0.84 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1KDM4EWHR1EHMT2 | |
| SCHEMBL13893912 | 0.82 | EHMT2 (0.60) | SMN1; SMN2ALDH1A1KDM4EPDE10AEHMT2 | |
| SCHEMBL3780652 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1KDM4EPDE10AEHMT2 | |
| SCHEMBL3527723 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1KDM4EPDE10AEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043991-C | Quinazoline deriv. | KYOWA HAKKO KOGYO KK (JP) | 1999-07-07 | — | — | CN | disclosed |
| CN-1134150-A | Quinazoline derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-10-23 | — | — | CN | disclosed |