Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | WHR1 | P49842 | 3/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | GLA | P06280 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2923197 | 0.87 | TLR9 (0.66) | SMN1; SMN2WHR1PIK3CDPIK3R1PIK3CA | |
| SCHEMBL27339271 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2WHR1PIK3CDPIK3R1PIK3CA | |
| SCHEMBL2923613 | 0.82 | PDGFRB (0.70) | — | |
| SCHEMBL22144610 | 0.80 | WHR1 (0.78) | SMN1; SMN2WHR1PIK3CDPIK3R1PIK3CA | |
| SCHEMBL22144613 | 0.80 | WHR1 (0.78) | SMN1; SMN2WHR1PIK3CDPIK3R1PIK3CA | |
| SCHEMBL12913438 | 0.78 | EHMT2 (0.58) | SMN1; SMN2KDM4EALDH1A1HPGDACHE | |
| SCHEMBL17122609 | 0.77 | ALDH1A1 (0.78) | SMN1; SMN2WHR1KDM4EALDH1A1HPGD | |
| SCHEMBL13893912 | 0.76 | EHMT2 (0.60) | SMN1; SMN2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13329880 | 0.76 | SMN1; SMN2 (0.72) | SMN1; SMN2WHR1KDM4EALDH1A1EHMT2 | |
| SCHEMBL13329878 | 0.76 | SMN1; SMN2 (0.72) | SMN1; SMN2WHR1KDM4EALDH1A1EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882717-B1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2010-09-08 | — | — | EP | disclosed |