Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDXK | O00764 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806636 | 0.88 | KDM4E (0.44) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27437788 | 0.86 | KDM4E (0.47) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27588200 | 0.85 | PDXK (0.42) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27606029 | 0.85 | PDXK (0.42) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27539162 | 0.85 | PDXK (0.42) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28031310 | 0.84 | KDM4E (0.40) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27954224 | 0.81 | LMNA (0.43) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1545975 | 0.80 | PDXK (0.53) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28517132 | 0.80 | KDM4E (0.53) | PDXKKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8904107 | 0.79 | PDXK (0.51) | PDXKKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1061408-A | Saturated hydroxyalkyl quinolinic acids as leukotriene antagonists | MERCK FROSST CANADA INC (US) | 1992-05-27 | — | — | CN | disclosed |