Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TKT | P29401 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13516628 | 0.81 | MAPK1 (0.37) | KDM4EMAPK1ALDH1A1BRD4MEN1 | |
| Hydrochloric Acid SCHEMBL6559450 | 0.79 | KDM4E (0.40) | KDM4EMAPK1ALDH1A1BRD4MEN1 | |
| SCHEMBL14556096 | 0.78 | KDM4E (0.57) | KDM4EMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL2733972 | 0.78 | TLR8 (0.40) | KDM4EMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL15318197 | 0.77 | KDM4E (0.37) | KDM4EMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL5255196 | 0.76 | — | — | |
| SCHEMBL6558389 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6559438 | 0.74 | KDM4E (0.38) | KDM4EMAPK1BRD4KMT2ASMN1; SMN2 | |
| SCHEMBL14556059 | 0.73 | HCAR2 (0.39) | KDM4EMAPK1TKTALDH1A1MEN1 | |
| SCHEMBL14556072 | 0.72 | LMNA (0.35) | KDM4EMAPK1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034591-A1 | DIAMINOPYRAZOLE-CONTAINING COMPOSITIONS FOR COLOURING KERATIN FIBRES, COLOURING PROCESS, NOVEL DIAMINOPYRAZOLES AND METHOD FOR THEIR PREPARATION | L'OREAL (FR) | 1996-11-07 | — | — | WO | disclosed |
| EP-0551291-A1 | THERAPEUTIC (PAF ANTAGONISTS) AGENTS | Pfizer Limited (GB) | 1993-07-21 | — | — | EP | disclosed |