SCHEMBL27339754

SCHEMBL27339754

CC(=O)c1c[c]ccc1Br

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
NPC1 O15118 5/20 0.31
RAB9A P51151 5/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31
MAOB P27338 1/20 0.31
MAOA P21397 1/20 0.31
SMN1; SMN2 Q16637 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232871 0.81 ALDH1A1 (0.37) ALDH1A1HPGDSMN1; SMN2
SCHEMBL2092525 0.80 ALDH1A1 (0.35) ALDH1A1CYP3A4HPGDMAPK1SMN1; SMN2
SCHEMBL5777262 0.79 ERN1 (0.38) ALDH1A1HPGDMAPK1
SCHEMBL5120316 0.79 TSHR (0.40) ALDH1A1CYP3A4HPGD
SCHEMBL1450340 0.78 SMN1; SMN2 (0.37) ALDH1A1CYP3A4HPGDMAPK1NPC1
SCHEMBL6326192 0.77 HPGD (0.41) ALDH1A1CYP3A4HPGDMAPK1MAOB
SCHEMBL443893 0.75 CES2 (0.35) ALDH1A1CYP3A4HPGDMAPK1MAOB
SCHEMBL7246452 0.75 SMN1; SMN2 (0.36) ALDH1A1CYP3A4HPGDMAPK1NPC1
SCHEMBL27999935 0.74 TSHR (0.50) ALDH1A1CYP3A4NPC1RAB9AMAOB
SCHEMBL6340582 0.72 SMN1; SMN2 (0.35) ALDH1A1HPGDMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1042907-A Herbicidal composition ICI PLC (GB) 1990-06-13 CN disclosed