SCHEMBL2734278

SCHEMBL2734278

CCCCCCCCCCCCCCCCCCCCCCCS

nearest known ligand 0.61

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
THRB P10828 1/20 0.61
DNM1 Q05193 8/20 0.47
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HSD17B10 Q99714 1/20 0.44
SLC22A1 O15245 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270812 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7616706 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28162 1.00
SCHEMBL51303 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL21048444 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL23668483 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5675255 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL15158032 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL20943436 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL2734408 1.00 TSHR (0.61) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210284786-A1 A FLEXIBLE FOAM FORMULATION AND METHOD OF PRODUCING THE SAME BASF SE (DE) 2021-09-16 US disclosed
CN-111233926-B Thiamine compound, preparation method and pharmaceutical composition thereof 上海日馨生物科技有限公司 2021-04-16 CN disclosed
CN-111233925-B Thiamine compound, preparation method and pharmaceutical composition thereof 上海日馨生物科技有限公司 2021-03-26 CN disclosed
US-10800895-B2 Polymer slides having hydrophobic small molecules STRATEC CONSUMABLES GmbH (AT) 2020-10-13 US disclosed
CN-111233926-A Thiamine compound, preparation method and pharmaceutical composition thereof 上海日馨生物科技有限公司 2020-06-05 CN disclosed
CN-111233925-A Thiamine compound, preparation method and pharmaceutical composition thereof 上海日馨生物科技有限公司 2020-06-05 CN disclosed
US-10611890-B2 Method of producing a polymer part and polymer part STRATEC CONSUMABLES GmbH (AT) 2020-04-07 US disclosed
EP-2792471-B1 Polymer parts STRATEC CONSUMABLES GmbH (AT) 2018-01-31 EP disclosed
US-9669049-B2 Compositions comprising gamma retrovirus vectors and methods of treating proliferative disorders TOCAGEN INC. (US) 2017-06-06 US disclosed
US-20170029587-A1 METHOD OF PRODUCING A POLYMER PART AND POLYMER PART STRATEC CONSUMABLES GmbH (AT) 2017-02-02 US disclosed
EP-2792471-A1 Polymer parts Sony DADC Austria AG (AT) 2014-10-22 EP disclosed
US-20140309375-A1 METHOD OF PRODUCING A POLYMER PART AND POLYMER PART SONY DADC AUSTRIA AG (AT) 2014-10-16 US disclosed
US-7906147-B2 superparamagnetic nanoparticles of iron coated with bilayer of molecules:(a) layer of oleic acid in direct contact with the iron particles; (b) a layer of Tween\"; bilayer of surface binding molecules and amphiphatic molecules; self-assembles; solubilizing; reducing toxicity; gold in MRI and tomography NANOPROBES, INC. (US) 2011-03-15 US disclosed
CN-1495293-B Surfactant enhanced protection method for preventing micromechanical component from electrically ageing ALTERA CORP 2010-10-27 CN disclosed
US-20080089836-A1 superparamagnetic nanoparticles of iron coated with bilayer of molecules:(a) layer of oleic acid in direct contact with the iron particles; (b) a layer of Tween\"; bilayer of surface binding molecules and amphiphatic molecules; self-assembles; solubilizing; reducing toxicity; gold in MRI and tomography NANOPROBES, INC. (US) 2008-04-17 US disclosed
CN-1495293-A Surfactant enhanced protection method for preventing micromechanical component from electrically ageing PTS 2004-05-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080089836-A1 superparamagnetic nanoparticles of iron coated with bilayer of molecules:(a) layer of oleic acid in direct contact with the iron particles; (b) a layer of Tween\"; bilayer of surface binding molecules and amphiphatic molecules; self-assembles; solubilizing; reducing toxicity; gold in MRI and tomography TFRC, FABP1, SCARB1 TSHR 1345/4885THRB 962/4885DNM1 268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.