Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL268976 | 0.92 | RAB9A (0.58) | NPC1RAB9APKMKDM4EMAPT | |
| SCHEMBL268977 | 0.92 | RAB9A (0.58) | NPC1RAB9APKMKDM4EMAPT | |
| SCHEMBL266760 | 0.86 | RAB9A (0.63) | NPC1RAB9APKMKDM4EMAPT | |
| SCHEMBL266759 | 0.86 | RAB9A (0.63) | NPC1RAB9APKMKDM4EMAPT | |
| SCHEMBL265728 | 0.84 | PKM (0.72) | NPC1RAB9APKMKDM4EMAPT | |
| SCHEMBL265729 | 0.84 | PKM (0.72) | NPC1RAB9APKMKDM4EMAPT | |
| SCHEMBL269255 | 0.84 | NPC1 (0.60) | NPC1RAB9APKMKDM4EMAPT | |
| SCHEMBL269254 | 0.84 | NPC1 (0.60) | NPC1RAB9APKMKDM4EMAPT | |
| SCHEMBL267147 | 0.83 | KDM4E (0.66) | NPC1RAB9APKMKDM4EMAPT | |
| SCHEMBL265290 | 0.83 | KDM4E (0.66) | NPC1RAB9APKMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134015-B2 | Compound inhibiting in vivo phosphorous transport and medicine containing the same | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-03-13 | — | — | US | disclosed |