Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24680534 | 0.84 | MAPT (0.53) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL29973088 | 0.83 | GAA (0.58) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL16720876 | 0.82 | MAPT (0.50) | ALDH1A1GAATDP1ALOX15MAPT | |
| SCHEMBL27887780 | 0.81 | ALDH1A1 (0.61) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL14053875 | 0.81 | MAPT (0.60) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL2440084 | 0.81 | ALDH1A1 (0.63) | ALDH1A1GAATDP1HTTALOX15 | |
| SCHEMBL16820312 | 0.80 | PTPRC (0.63) | ALDH1A1TDP1HTTMAPTKDM4E | |
| SCHEMBL27024567 | 0.80 | GAA (0.61) | ALDH1A1GAATDP1HTTALOX15 | |
| Benzene SCHEMBL28417037 | 0.78 | FABP4 (0.55) | ALDH1A1GAATDP1ALOX15MAPT | |
| SCHEMBL588648 | 0.78 | FABP4 (0.55) | ALDH1A1GAATDP1ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043766-C | Indole derivative and preparation and pharmaceutical using of same | TORAY INDUSTRIES (JP) | 1999-06-23 | — | — | CN | disclosed |
| CN-1092425-A | Indole derivatives, its manufacture method and medicinal use thereof | TORAY INDUSTRIES (JP) | 1994-09-21 | — | — | CN | disclosed |