Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680840 | 1.00 | AR (0.41) | ARUSP30KDM4EKMT2AALDH1A1 | |
| SCHEMBL24319568 | 0.91 | KDM4E (0.42) | USP30KDM4EKMT2AALDH1A1CHRM4 | |
| SCHEMBL27132331 | 0.86 | AR (0.44) | ARNOTUM | |
| SCHEMBL26969633 | 0.86 | AR (0.44) | ARNOTUM | |
| SCHEMBL30680830 | 0.84 | CHRM4 (0.42) | ARUSP30KDM4EKMT2AALDH1A1 | |
| SCHEMBL27345249 | 0.84 | CHRM4 (0.42) | ARUSP30KDM4EKMT2AALDH1A1 | |
| SCHEMBL27345252 | 0.84 | CHRM4 (0.42) | ARUSP30KDM4EKMT2AALDH1A1 | |
| SCHEMBL26649322 | 0.84 | SIRT6 (0.42) | ARKDM4EKMT2AALDH1A1CHRM4 | |
| SCHEMBL24207038 | 0.83 | USP30 (0.44) | ARUSP30KDM4EKMT2AALDH1A1 | |
| SCHEMBL26969675 | 0.83 | USP30 (0.44) | ARUSP30KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245150-A1 | KAT6 TARGETING COMPOUNDS WITH UBIQUITIN LIGASE BINDING MOIETY | PRELUDE THERAPEUTICS INCORPORATED (US) | 2023-12-21 | — | — | WO | disclosed |