Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680830 | 1.00 | CHRM4 (0.42) | CHRM4ARUSP30KDM4EKMT2A | |
| SCHEMBL27345249 | 1.00 | CHRM4 (0.42) | CHRM4ARUSP30KDM4EKMT2A | |
| SCHEMBL24319287 | 0.91 | KDM4E (0.41) | CHRM4USP30KDM4EKMT2ANR1H2 | |
| SCHEMBL27123954 | 0.90 | CHRM4 (0.42) | CHRM4ARUSP30NOTUM | |
| SCHEMBL26969638 | 0.90 | CHRM4 (0.42) | CHRM4ARUSP30NOTUM | |
| SCHEMBL27345241 | 0.84 | AR (0.41) | CHRM4ARUSP30KDM4EKMT2A | |
| SCHEMBL26648905 | 0.84 | SIRT6 (0.41) | CHRM4ARKDM4EKMT2AALDH1A1 | |
| SCHEMBL30680840 | 0.84 | AR (0.41) | CHRM4ARUSP30KDM4EKMT2A | |
| SCHEMBL24207038 | 0.81 | USP30 (0.44) | CHRM4ARUSP30KDM4EKMT2A | |
| SCHEMBL27345261 | 0.81 | ALDH1A1 (0.36) | USP30KDM4ENR1H2NR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245150-A1 | KAT6 TARGETING COMPOUNDS WITH UBIQUITIN LIGASE BINDING MOIETY | PRELUDE THERAPEUTICS INCORPORATED (US) | 2023-12-21 | — | — | WO | disclosed |