Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PPIA | P62937 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772996 | 1.00 | HTT (0.71) | HTTTSHRPPIABRD4NPC1 | |
| SCHEMBL9502644 | 0.88 | HTT (0.71) | HTTTSHRPPIABRD4NPC1 | |
| SCHEMBL28000002 | 0.85 | HTT (0.67) | HTTTSHRPPIABRD4NPC1 | |
| SCHEMBL12426304 | 0.84 | CNR2 (0.60) | HTTTSHRNPC1RAB9AMAPT | |
| SCHEMBL28137220 | 0.84 | HTT (0.65) | HTTTSHRPPIABRD4NPC1 | |
| SCHEMBL1179791 | 0.84 | HTT (0.65) | HTTTSHRPPIABRD4NPC1 | |
| SCHEMBL18640752 | 0.83 | HTT (1.00) | HTTTSHRPPIANPC1RAB9A | |
| SCHEMBL4611494 | 0.82 | HTT (0.64) | HTTTSHRPPIABRD4NPC1 | |
| SCHEMBL6612663 | 0.81 | ALDH1A1 (0.68) | HTTTSHRPPIABRD4NPC1 | |
| SCHEMBL15639452 | 0.81 | HTT (0.62) | HTTTSHRPPIABRD4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043344-C | New heterocyclic compounds | KRONSEDER MASCHF KRONES (JP) | 1999-05-12 | — | — | CN | disclosed |