Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PPIA | P62937 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18640732 | 0.86 | HTT (0.76) | HTTRAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL27345451 | 0.83 | HTT (0.71) | HTTTP53RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL9502644 | 0.83 | HTT (0.71) | HTTTP53RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL30772996 | 0.83 | HTT (0.71) | HTTTP53RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL16675446 | 0.82 | HTT (0.69) | HTTRAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL23566366 | 0.82 | HTT (0.69) | HTTRAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL18640787 | 0.82 | HTT (0.69) | HTTRAB9AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11833609 | 0.81 | HTT (0.68) | HTTRAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28000002 | 0.80 | HTT (0.67) | HTTTP53RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL3820618 | 0.80 | HTT (0.66) | HTTRAB9AALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362436-B1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIV ANTWERPEN (BE) | 2021-06-30 | — | — | EP | disclosed |
| EP-3362436-A1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | Universiteit Antwerpen (BE) | 2018-08-22 | — | — | EP | disclosed |
| WO-2017046133-A1 | PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2017-03-23 | — | — | WO | disclosed |