Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516719 | 0.88 | EGFR (0.48) | EGFRDGAT1CSF1RNTRK1NTRK2 | |
| SCHEMBL27345689 | 0.86 | EGFR (0.46) | EGFRSLC6A4DGAT1CSF1RNTRK1 | |
| SCHEMBL27345601 | 0.85 | EGFR (0.48) | EGFRDGAT1CSF1RLPLLIPG | |
| SCHEMBL25179630 | 0.85 | DGAT1 (0.46) | EGFRDGAT1CSF1RNTRK1NTRK2 | |
| SCHEMBL29362049 | 0.85 | DGAT1 (0.46) | EGFRDGAT1CSF1RNTRK1NTRK2 | |
| SCHEMBL27345685 | 0.84 | CSF1R (0.46) | EGFRDGAT1CSF1RNTRK1NTRK2 | |
| SCHEMBL27345776 | 0.84 | HIF1A (0.39) | EGFRSLC6A4DGAT1CSF1RHIF1A | |
| SCHEMBL27345779 | 0.83 | EGFR (0.48) | EGFRDGAT1CSF1RHIF1ALPL | |
| SCHEMBL17129080 | 0.83 | DGAT1 (0.52) | DGAT1HIF1ALPLLIPGMRGPRX4 | |
| SCHEMBL31065363 | 0.83 | DGAT1 (0.47) | EGFRSLC6A4DGAT1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133605-A1 | SUBSTITUTED 3,7-DIHYDRO-1 H-PURINE-2,6-DIONES AND USE THEREOF | INVIOS GMBH (AT) | 2024-06-27 | — | — | WO | disclosed |