Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 3/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25944367 | 0.77 | ATR (0.40) | ATRLCKMAPKAPK2NAMPTCYP17A1 | |
| SCHEMBL27319995 | 0.73 | CHUK (0.37) | CA2 | |
| SCHEMBL7688627 | 0.73 | MAPKAPK2 (0.39) | ATRLCKMAPKAPK2NAMPTCYP17A1 | |
| SCHEMBL31722807 | 0.73 | ATR (0.38) | ATRLCKMAPKAPK2NAMPTTRPA1 | |
| SCHEMBL18236165 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL24608566 | 0.72 | RAB9A (0.40) | ATRLCKMAPKAPK2NAMPTCYP17A1 | |
| SCHEMBL9109986 | 0.72 | CYP17A1 (0.41) | ATRNAMPTCYP17A1 | |
| SCHEMBL3269413 | 0.71 | ATR (0.41) | ATRLCKMAPKAPK2NAMPTTRPA1 | |
| SCHEMBL20672997 | 0.71 | ATR (0.39) | ATRLCKCYP17A1CA1CA2 | |
| SCHEMBL22110342 | 0.70 | MAPKAPK2 (0.47) | ATRMAPKAPK2NAMPTTRPA1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046286-C | Novel cephem derivatives | MEIJI SEIKA CO (JP) | 1999-11-10 | — | — | CN | disclosed |
| CN-1114507-A | Novel cephem derivatives | MEIJI SEIKA CO (JP) | 1996-01-03 | — | — | CN | disclosed |