SCHEMBL27345646

SCHEMBL27345646

CC(C)OC=O.Nc1ccc(F)cc1F

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
KEAP1 Q14145 1/20 0.36
MEN1 O00255 2/20 0.34
HPGD P15428 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HDAC1 Q13547 2/20 0.33
HDAC6 Q9UBN7 1/20 0.33
IDO1 P14902 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid Methyl Ester SCHEMBL27621281 0.82 ALDH1A1 (0.65) ALDH1A1CA12CA1CA2CA4
Formic Acid SCHEMBL28834640 0.76 ALDH1A1 (0.74) ALDH1A1CA12CA1CA2CA4
SCHEMBL11425 0.75
SCHEMBL29595875 0.75
Fluoride SCHEMBL29165726 0.73 ALDH1A1 (0.94) ALDH1A1CA12CA1CA2CA4
Hydrochloric Acid SCHEMBL3851075 0.73 ALDH1A1 (0.94) ALDH1A1CA12CA1CA2CA4
Methane SCHEMBL22289605 0.73 ALDH1A1 (0.94) ALDH1A1CA12CA1CA2CA4
Hydrochloric Acid SCHEMBL7125109 0.73 ALDH1A1 (0.94) ALDH1A1CA12CA1CA2CA4
Allyl Formate SCHEMBL27294340 0.71 ALDH1A1 (0.53) ALDH1A1CA12CA1CA2CA4
Cyanide SCHEMBL27761725 0.69 ALDH1A1 (0.85) ALDH1A1CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1049846-A Glutarimide with weeding activity ROHM & HAAS (US) 1991-03-13 CN disclosed