Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.31 |
| ▸ | IDH1 | O75874 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27346362 | 0.81 | KCNH2 (0.32) | KDM4ECXCR4 | |
| SCHEMBL27346579 | 0.78 | MAP3K12 (0.31) | KDM4ECXCR4 | |
| SCHEMBL27346564 | 0.78 | CHRM4 (0.37) | — | |
| SCHEMBL27346072 | 0.78 | PTGS2 (0.34) | IDH1 | |
| SCHEMBL27346552 | 0.78 | NR1H2 (0.38) | IDH1 | |
| SCHEMBL27346544 | 0.76 | GRIN2B (0.31) | GRIN2B | |
| SCHEMBL26065735 | 0.72 | HTR2A (0.33) | KDM4ECXCR4 | |
| SCHEMBL27345826 | 0.72 | TRPV4 (0.45) | KDM4E | |
| SCHEMBL25890475 | 0.71 | HTR2A (0.33) | KDM4ECXCR4 | |
| SCHEMBL22924540 | 0.69 | KDM4E (0.50) | KDM4ECXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015503-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |