Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938470 | 0.88 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL6377242 | 0.86 | IDO1 (0.47) | IDO1AKR1B1ALDH1A1HSPA5CA12 | |
| SCHEMBL2623832 | 0.85 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL2295732 | 0.85 | IDO1 (0.53) | IDO1AKR1B1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11064859 | 0.85 | IDO1 (0.53) | IDO1AKR1B1ALDH1A1HSPA5TYR | |
| SCHEMBL29781146 | 0.84 | CA12 (0.47) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL4577937 | 0.83 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDNPSR1HSD17B10 | |
| SCHEMBL10956714 | 0.83 | IDO1 (0.52) | IDO1AKR1B1ALDH1A1HSPA5CA12 | |
| SCHEMBL28063219 | 0.83 | L3MBTL1 (0.50) | IDO1AKR1B1KDM4EIAPPTSHR | |
| SCHEMBL4352847 | 0.82 | TYR (0.56) | AKR1B1KDM4EHSPA5CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663293-B | Quinoline-carboxamide derivatives as p2y12 antagonists | SANOFI AVENTIS SPA | 2013-07-31 | — | — | CN | disclosed |
| CN-101723905-B | Synthesis method of 2- (2- (6- (2-cyanophenoxy) pyrimidine-4-oxy) phenyl) methyl acetate | DS CHEMPHY INC | 2011-09-14 | — | — | CN | disclosed |
| CN-101723905-A | Synthesis method of 2- (2- (6- (2-cyanophenoxy) pyrimidine-4-oxy) phenyl) methyl acetate | DALIAN KAIFEI FINE CHEMICALS C | 2010-06-09 | — | — | CN | disclosed |
| CN-101054345-B | Novel bensophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD | 2010-06-02 | — | — | CN | disclosed |
| CN-1602291-B | Novel benzophenone derivative or salt thereof | TOYAMA CHEMICAL CO LTD | 2010-05-12 | — | — | CN | disclosed |
| CN-101679216-A | Novel 3-phenylpropionic acid derivatives as activators for receptors of the PPAR type, process for their preparation and their use in cosmetic or pharmaceutical compositions | GALDERMA RES & DEV | 2010-03-24 | — | — | CN | disclosed |
| CN-101663293-A | Quinoline-carboxamide derivatives as p2y12 antagonists | SANOFI AVENTIS | 2010-03-03 | — | — | CN | disclosed |
| CN-101402562-A | Novel benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2009-04-08 | — | — | CN | disclosed |
| CN-101054345-A | Novel bensophenone derivatives or salts thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-10-17 | — | — | CN | disclosed |
| CN-1662487-A | Amide linker peroxisome proliferator-activated receptor modulators | LILLY CO ELI (US) | 2005-08-31 | — | — | CN | disclosed |
| CN-1602291-A | Novel benzophenone derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2005-03-30 | — | — | CN | disclosed |
| CN-1164579-C | Thiazole and oxazole derivatives and their pharmaceutical use | — | 2004-09-01 | — | — | CN | disclosed |
| CN-1358179-A | Thiazole and oxazole derivatives and their pharmaceutical use | GLAXO GROUP LTD (GB) | 2002-07-10 | — | — | CN | disclosed |
| CN-1291214-A | Compositions comprising fluoropolymers and amide functional ultraviolet light absorbers | MINNESOTA MINING & MFG (US) | 2001-04-11 | — | — | CN | disclosed |
| CN-1035001-C | Substituted phenyl phenol leukotriene antagonists | LILLY CO ELI (US) | 1997-05-28 | — | — | CN | disclosed |
| CN-1088906-A | The phenyl phenol leukotriene antagonists that replaces | LILLY CO ELI (US) | 1994-07-06 | — | — | CN | disclosed |