Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYBB | P04839 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344516 | 0.93 | ALOX5 (0.48) | ACE2ALOX5MAPTALOX15ALDH1A1 | |
| SCHEMBL27344785 | 0.81 | ALOX5 (0.51) | ALOX5MAPTALOX15ALDH1A1HTR7 | |
| SCHEMBL4859644 | 0.79 | ALOX5 (0.74) | ALOX5MAPTALOX15HTR7HTR2B | |
| SCHEMBL27344285 | 0.79 | ACE2 (0.54) | ACE2ALOX5MAPTALOX15ALDH1A1 | |
| SCHEMBL27344712 | 0.78 | ALOX5 (0.51) | ALOX5MAPTALOX15ALDH1A1HTR7 | |
| SCHEMBL27344790 | 0.77 | ABL1 (0.54) | ALOX5ABL1 | |
| SCHEMBL29636456 | 0.75 | ALOX5 (0.59) | ACE2ALOX5MAPTJUNNFKB1 | |
| SCHEMBL11535935 | 0.75 | ALOX5 (0.59) | ACE2ALOX5MAPTJUNNFKB1 | |
| SCHEMBL27344709 | 0.74 | ALOX5 (0.51) | ALOX5MAPTALOX15ALDH1A1HTR7 | |
| SCHEMBL30811571 | 0.74 | ACE2 (0.49) | ACE2ALOX5MAPTALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |