Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYBB | P04839 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344712 | 0.93 | ALOX5 (0.51) | ALOX5HTR2BHTR7AHRMEN1 | |
| SCHEMBL4859644 | 0.82 | ALOX5 (0.74) | ALOX5HTR2BHTR7MEN1MAPT | |
| SCHEMBL27344516 | 0.80 | ALOX5 (0.48) | ALOX5HTR2BHTR7MEN1MAPT | |
| SCHEMBL27344785 | 0.78 | ALOX5 (0.51) | ALOX5HTR2BHTR7MEN1MAPT | |
| SCHEMBL17396556 | 0.78 | AHR (0.58) | ALOX5HTR2BHTR7AHRNOX1 | |
| SCHEMBL28399287 | 0.77 | ALOX5 (0.58) | ALOX5HTR2BHTR7MAPTGAA | |
| SCHEMBL27344790 | 0.77 | ABL1 (0.54) | ALOX5 | |
| SCHEMBL28403621 | 0.75 | ALOX5 (0.79) | ALOX5HTR2BHTR7MAPTGAA | |
| SCHEMBL27345997 | 0.74 | ACE2 (0.50) | ALOX5HTR2BHTR7MEN1MAPT | |
| SCHEMBL8725779 | 0.73 | ALOX5 (0.65) | ALOX5HTR2BHTR7AHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |