SCHEMBL27346173

SCHEMBL27346173

Cc1cc(S(=O)(=O)N2C[C@H]3CNC[C@H]3C2)n(C)n1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CHRNA4 P43681 15/20 0.38
▸ CHRNB2 P17787 9/20 0.36
▸ CHRNB4 P30926 9/20 0.36
▸ CHRNA3 P32297 9/20 0.36
▸ CHRNA7 P36544 2/20 0.33
▸ HCRTR1 O43613 2/20 0.32
▸ HCRTR2 O43614 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30719506 0.76 MEN1 (0.33) —
SCHEMBL27346137 0.76 MEN1 (0.33) —
SCHEMBL27346165 0.74 NR1H2 (0.41) —
SCHEMBL2998525 0.69 SMN1; SMN2 (0.40) —
SCHEMBL30719500 0.69 IRAK4 (0.34) —
SCHEMBL27345089 0.69 IRAK4 (0.34) —
SCHEMBL25363181 0.68 TSHR (0.37) —
SCHEMBL24209118 0.67 PKM (0.56) —
SCHEMBL25026249 0.67 PKM (0.56) —
SCHEMBL16030986 0.67 SMN1; SMN2 (0.38) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554934-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-21 — — EP disclosed
CN-119731160-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-03-28 — — CN disclosed
WO-2024015503-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-18 — — WO disclosed
WO-2024015503-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-18 — — WO disclosed
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