SCHEMBL27346137

SCHEMBL27346137

Cc1cc(S(=O)(=O)N2C[C@H]3CN(C4CCOCC4)C[C@H]3C2)n(C)n1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ PIK3CA P42336 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ PDE7A Q13946 2/20 0.32
▸ ALDH1A1 P00352 3/20 0.32
▸ PKM P14618 2/20 0.32
▸ TP53 P04637 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ TDP2 O95551 1/20 0.30
▸ CHRM2 P08172 1/20 0.30
▸ CHRM4 P08173 1/20 0.30
▸ CHRM5 P08912 1/20 0.30
▸ CHRM1 P11229 1/20 0.30
▸ CHRM3 P20309 1/20 0.30
▸ KCNH2 Q12809 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30719506 1.00 MEN1 (0.33) MEN1KMT2AATMPIK3CAPOLB
SCHEMBL27346508 0.83 CTSK (0.39) MEN1KMT2APIK3CAHPGDALDH1A1
SCHEMBL27346368 0.83 CTSK (0.39) MEN1KMT2APIK3CAHPGDALDH1A1
SCHEMBL25371519 0.81 HRH3 (0.35) MEN1KMT2AATMPOLBHPGD
SCHEMBL30719500 0.78 IRAK4 (0.34) MEN1KMT2ACHRM2CHRM4
SCHEMBL27345089 0.78 IRAK4 (0.34) MEN1KMT2ACHRM2CHRM4
SCHEMBL27346173 0.76 CHRNA4 (0.38) —
SCHEMBL26066065 0.76 HPGD (0.38) MEN1KMT2AHPGDPDE7AALDH1A1
SCHEMBL27346134 0.75 — —
SCHEMBL26065421 0.75 HPGD (0.37) MEN1KMT2AHPGDPDE7AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4554934-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-21 — — EP claimed
CN-119731160-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-03-28 — — CN claimed
WO-2024015503-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-18 — — WO claimed
EP-4554934-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF Biogen MA Inc. (US) 2025-05-21 — — EP disclosed
CN-119731160-A Emopanamide binding protein inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-03-28 — — CN disclosed
WO-2024015503-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-18 — — WO disclosed
WO-2024015503-A1 EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF BIOGEN MA INC. (US) 2024-01-18 — — WO disclosed
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