Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Fumarate SCHEMBL1067038 | 0.89 | HCAR2 (0.80) | HCAR2MAPTALDH1A1HPGDTSHR | |
| Ethyl Fumarate SCHEMBL16176170 | 0.89 | HCAR2 (0.65) | HCAR2MAPTALDH1A1HPGDTSHR | |
| Ethyl Fumarate SCHEMBL28185445 | 0.87 | HCAR2 (0.83) | HCAR2MAPTALDH1A1KEAP1NFE2L2 | |
| Ethyl Fumarate SCHEMBL4179969 | 0.87 | HCAR2 (0.83) | HCAR2MAPTALDH1A1KEAP1NFE2L2 | |
| Ethyl Fumarate SCHEMBL2776691 | 0.87 | HCAR2 (0.83) | HCAR2MAPTALDH1A1LMNAMDM2 | |
| Ethyl Fumarate SCHEMBL9467940 | 0.87 | HCAR2 (0.83) | HCAR2MAPTALDH1A1LMNAMDM2 | |
| Ethyl Fumarate SCHEMBL11309874 | 0.87 | HCAR2 (0.83) | HCAR2MAPTALDH1A1LMNAMDM2 | |
| Ethyl Fumarate SCHEMBL4179975 | 0.87 | HCAR2 (0.83) | HCAR2MAPTALDH1A1KEAP1NFE2L2 | |
| Ethyl Fumarate SCHEMBL433387 | 0.87 | HCAR2 (0.91) | HCAR2MAPTALDH1A1LMNAMDM2 | |
| Ethyl Fumarate SCHEMBL28242388 | 0.87 | HCAR2 (0.91) | HCAR2MAPTALDH1A1LMNAMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031885-C | Thermoplastic elastomeric compositions | DU PONT (US) | 1996-05-29 | — | — | CN | disclosed |