Ethyl Fumarate

Ethyl Fumarate

SCHEMBL433387

C=C.CCOC(=O)C=CC(=O)O

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 9/20 0.91
MAPT P10636 5/20 0.46
ATM Q13315 1/20 0.45
ALDH1A1 P00352 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
LMNA P02545 2/20 0.41
MDM2 Q00987 2/20 0.41
MDM4 O15151 1/20 0.41
TP53 P04637 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Fumarate SCHEMBL28242388 1.00 HCAR2 (0.91) HCAR2MAPTATMALDH1A1NPSR1
Ethyl Fumarate SCHEMBL433385 1.00 HCAR2 (0.91) HCAR2MAPTATMALDH1A1NPSR1
Diethyl Maleate SCHEMBL10994278 0.95 HCAR2 (1.00) HCAR2MAPTATMALDH1A1NPSR1
Diethyl Maleate SCHEMBL9193839 0.95 HCAR2 (1.00) HCAR2MAPTATMALDH1A1NPSR1
Ethyl Fumarate SCHEMBL60568 0.95 HCAR2 (1.00) HCAR2MAPTATMALDH1A1NPSR1
Ethyl Fumarate SCHEMBL1133858 0.95 HCAR2 (1.00) HCAR2MAPTATMALDH1A1NPSR1
Diethyl Maleate SCHEMBL10994275 0.95 HCAR2 (1.00) HCAR2MAPTATMALDH1A1NPSR1
Diethyl Maleate SCHEMBL19873394 0.95 HCAR2 (1.00) HCAR2MAPTATMALDH1A1NPSR1
Ethyl Fumarate SCHEMBL1133862 0.95 HCAR2 (1.00) HCAR2MAPTATMALDH1A1NPSR1
Ethyl Fumarate SCHEMBL60569 0.95 HCAR2 (1.00) HCAR2MAPTATMALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US claimed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP claimed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US claimed
CN-120005240-A Multilayer film, polyimide film and cover film package 杜邦电子公司 2025-05-16 CN disclosed
CN-111212731-B Composite material with direct bonding between rubber and foam 陶氏环球技术有限责任公司 2022-06-21 CN disclosed
US-11203192-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2021-12-21 US disclosed
US-10844184-B2 Matte finish polyimide films and methods relating thereto DUPONT ELECTRONICS, INC. (US) 2020-11-24 US disclosed
US-20190263099-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2019-08-29 US disclosed
US-10336045-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2019-07-02 US disclosed
US-20180163006-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-06-14 US disclosed
US-9926415-B2 Matte finish polyimide films and methods relating thereto E I DU PONT DE NEMOURS AND COMPANY (US) 2018-03-27 US disclosed
US-20110177321-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-21 US disclosed
WO-2011019899-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 WO disclosed
US-20110039085-A1 PIGMENTED POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-17 US disclosed
WO-2011017291-A1 MATTE FINISH POLYIMIDE FILMS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-10 WO disclosed
WO-2010101822-A1 MULTILAYER FILM FOR ELECTRONIC CIRCUITRY APPLICATIONS AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-09-10 WO disclosed
US-20100108140-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-05-06 US disclosed
EP-2124262-A2 Layer arrangement being thermally conductive and electrically isolating E. I. du Pont de Nemours and Company (US) 2009-11-25 EP disclosed
US-20090229809-A1 DEVICE CAPABLE OF THERMALLY COOLING WHILE ELECTRICALLY INSULATING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-17 US disclosed
US-20070105984-A1 Composition comprising cellulose and polyvinyl chloride polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-05-10 US disclosed