Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.55 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066292 | 0.86 | CYP4F2 (0.63) | LOXL2CYP4F2CYP4A11ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL926826 | 0.85 | CYP4F2 (0.61) | LOXL2CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL6795893 | 0.83 | TDP1 (0.50) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| Ethyne SCHEMBL28024446 | 0.83 | CYP4F2 (0.59) | LOXL2CYP4F2CYP4A11ALDH1A1GAA | |
| Acetone SCHEMBL28148704 | 0.83 | CYP4F2 (0.59) | LOXL2CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL10140460 | 0.83 | CYP4F2 (0.50) | LOXL2CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL5802908 | 0.83 | CA2 (0.50) | CYP4F2CYP4A11ALDH1A1GAAGFER | |
| SCHEMBL5431221 | 0.81 | HTT (0.62) | ALDH1A1GAAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL6025472 | 0.81 | ALDH1A1 (0.56) | CYP4F2CYP4A11ALDH1A1LMNA | |
| SCHEMBL10829361 | 0.81 | CYP4F2 (0.49) | CYP4F2CYP4A11ALDH1A1GAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056602-C | Esters and amides as PLA2 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-20 | — | — | CN | disclosed |
| CN-1197450-A | Esters and amides as phospholipase A2 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-28 | — | — | CN | disclosed |