SCHEMBL27348447

SCHEMBL27348447

OC1c2ccccc2-c2cccc(C3=CC=CC3)c21

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 2/20 0.33
HTR7 P34969 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GPR3 P46089 1/20 0.31
POLB P06746 1/20 0.30
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9244149 0.83 GPR3 (0.32) GPR3
SCHEMBL9659749 0.83 GPR3 (0.32) GPR3
SCHEMBL6139097 0.81 GPR3 (0.31) GPR3
SCHEMBL3900299 0.81 GPR3 (0.31) GPR3
Iodide SCHEMBL7921882 0.80 GPR3 (0.30) GPR3
Hydrochloric Acid SCHEMBL6469639 0.80 GPR3 (0.30) GPR3
Bromide SCHEMBL7929245 0.80 GPR3 (0.30) GPR3
Hydrochloric Acid SCHEMBL8458988 0.80 GPR3 (0.30) GPR3
Bromide SCHEMBL7939130 0.80 GPR3 (0.30) GPR3
Hydrochloric Acid SCHEMBL3041072 0.80 GPR3 (0.30) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1154668-C Dicyclopentradiene diene compound 2004-06-23 CN claimed
CN-1263894-A Dicyclopentradiene diene compound DOW CHEMICAL CO (US) 2000-08-23 CN claimed
CN-1156997-A Dicyclopentadienyl diene complexes DOW CHEMICAL CO (US) 1997-08-13 CN claimed
CN-102015787-B Polyalphaolefins and methods of forming polyalphaolefins CHEMTURA CORP 2013-06-19 CN disclosed
CN-102057022-A Pour point depressant for hydrocarbon compositions EXXONMOBIL CHEM PATENTS INC 2011-05-11 CN disclosed
CN-102015787-A Polyalphaolefins and methods of forming polyalphaolefins CHEMTURA CORP 2011-04-13 CN disclosed
CN-1176093-C Dicyclo-pentadienyl-diene matches 2004-11-17 CN disclosed
CN-1154668-C Dicyclopentradiene diene compound 2004-06-23 CN disclosed
CN-1058015-C Dicyclopentadienyl diene complexes DOW CHEMICAL CO (US) 2000-11-01 CN disclosed
CN-1263894-A Dicyclopentradiene diene compound DOW CHEMICAL CO (US) 2000-08-23 CN disclosed
CN-1260350-A Dicyclo-pentadienyl-diene matches DOW CHEMIAL CO (US) 2000-07-19 CN disclosed
CN-1156997-A Dicyclopentadienyl diene complexes DOW CHEMICAL CO (US) 1997-08-13 CN disclosed