Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7921882 | 0.97 | GPR3 (0.30) | GPR3 | |
| Bromide SCHEMBL7939130 | 0.97 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL3037838 | 0.82 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL524857 | 0.82 | GPR3 (0.30) | GPR3 | |
| SCHEMBL9659749 | 0.81 | GPR3 (0.32) | GPR3 | |
| SCHEMBL9244149 | 0.81 | GPR3 (0.32) | GPR3 | |
| SCHEMBL27348447 | 0.80 | HTR2B (0.33) | GPR3 | |
| SCHEMBL3900299 | 0.80 | GPR3 (0.31) | GPR3 | |
| SCHEMBL6139097 | 0.80 | GPR3 (0.31) | GPR3 | |
| Hydrochloric Acid SCHEMBL7790280 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127305-A | Catalyst and process for polymerizing alpha-olefins | ENICHEM S.P.A (IT) | 2000-10-03 | — | — | US | claimed |
| EP-0588404-B1 | Catalyst and process for polymerizing alpha-olefins | ENICHEM SPA (IT) | 1997-06-18 | — | — | EP | claimed |
| EP-0588404-A2 | Catalyst and process for polymerizing alpha-olefins | ENICHEM S.p.A. (IT) | 1994-03-23 | — | — | EP | claimed |
| US-7785735-B2 | Microporous composite membrane and its producing method and use | TONEN CHEMICAL CORPORATION (JP) | 2010-08-31 | — | — | US | disclosed |
| EP-1693408-B1 | MICROPOROUS COMPOSITE FILM, PROCESS FOR PRODUCING THE SAME, AND USE | TONEN SEKIYUKAGAKU KK (JP) | 2010-04-14 | — | — | EP | disclosed |
| CN-101688046-A | Flame-retardant silane-crosslinked olefin resin composition, insulated wire, and method for production of flame-retardant silane-crosslinked olefin resin | AUTONETWORKS TECHNOLOGIES LTD | 2010-03-31 | — | — | CN | disclosed |
| US-20070128512-A1 | Microporous composite membrane and its producing method and use | TORAY INDUSTRIES, INC. (JP) | 2007-06-07 | — | — | US | disclosed |
| EP-1693408-A1 | MICROPOROUS COMPOSITE FILM, PROCESS FOR PRODUCING THE SAME, AND USE | Tonen Chemical Corporation (JP) | 2006-08-23 | — | — | EP | disclosed |
| EP-0881232-B1 | Catalyst for olefin polymerization and process for the production of an olefin polymer | TOSOH CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1155051-B1 | COMPOSITIONS OF PREACTIVATED UNSUPPORTED CATALYST HAVING A GIVEN CONCENTRATION AND METHODS OF USING THEM | UNION CARBIDE CHEM PLASTIC (US) | 2004-10-13 | — | — | EP | disclosed |
| EP-0946610-B1 | HIGH ACTIVITY METALLOCENE POLYMERIZATION PROCESS | EXXONMOBIL CHEM PATENTS INC (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-0588404-B1 | Catalyst and process for polymerizing alpha-olefins | ENICHEM SPA (IT) | 1997-06-18 | — | — | EP | disclosed |
| CN-1140720-A | Syndiotactic selective compound metallocene catalyst | CHINA PETROCHEMICAL CORP (CN) | 1997-01-22 | — | — | CN | disclosed |
| CN-1031580-C | Catalyst and process for polymerization and copolymerization of alpha-olefins | ENICHEM ANIC SPA (IT) | 1996-04-17 | — | — | CN | disclosed |
| EP-0588404-A2 | Catalyst and process for polymerizing alpha-olefins | ENICHEM S.p.A. (IT) | 1994-03-23 | — | — | EP | disclosed |
| EP-0422703-B1 | CATALYST AND PROCESS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF ALPHA-OLEFINS | Enichem Anic S.r.l. (IT) | 1993-06-30 | — | — | EP | disclosed |
| US-5128295-A | Hafnium-titanium-zirconium compound with trialkylaluminum and distannoxane | ENICHEM ANIC S.P.A. (IT) | 1992-07-07 | — | — | US | disclosed |
| CN-1059532-A | PROPYLENE COPOLYMER | MITSUI TOATSU CHEMICALS (JP) | 1992-03-18 | — | — | CN | disclosed |
| CN-1051363-A | The catalyzer of alpha-olefine polymerizing and copolymerization and method | ENICHEM ANIC SPA (IT) | 1991-05-15 | — | — | CN | disclosed |
| EP-0422703-A1 | Catalyst and process for the polymerization and copolymerization of alpha-olefins | Enichem Anic S.r.l. (IT) | 1991-04-17 | — | — | EP | disclosed |