SCHEMBL27348593

SCHEMBL27348593

FNc1ccc(N2CCOCC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
MAPT P10636 8/20 0.52
ALDH1A1 P00352 5/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
HTT P42858 3/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
CYP1A2 P05177 1/20 0.52
GAA P10253 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
KDM4E B2RXH2 2/20 0.50
TP53 P04637 2/20 0.50
MAPK1 P28482 2/20 0.50
USP2 O75604 1/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ALOX12 P18054 1/20 0.50
HDAC8 Q9BY41 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28754243 0.98 MAPT (0.50) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL7066138 0.83 LMNA (0.56) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL7980595 0.83 MAPT (0.62) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL9093746 0.82 LMNA (0.71) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL28054164 0.81 GFER (0.55) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL27970512 0.80 LMNA (0.53) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL3080226 0.79 HDAC8 (0.57) LMNAMAPTALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL5339521 0.79 LMNA (0.52) LMNAMAPTALDH1A1MEN1KMT2A
SCHEMBL487498 0.79 GAA (0.56) LMNAMAPTALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL28349769 0.78 GAA (0.54) LMNAMAPTALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115389661-A Method for detecting genotoxic impurities in linezolid glucose injection 华润双鹤药业股份有限公司 2022-11-25 CN disclosed
CN-103664813-A Preparation method of linezolid SHENYANG J & HEALTH PHARAMACEUTICAL CO LTD 2014-03-26 CN disclosed
CN-1057087-C Substituted oxazine and thiazine oxazolidinone antimicrobials UPJOHN CO (US) 2000-10-04 CN disclosed
CN-1130379-A Substituted oxazine and thiazine oxazolidinone antimicrobials UPJOHN CO (US) 1996-09-04 CN disclosed