Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | C5 | P01031 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849248 | 0.98 | PPARA (0.54) | PPARANOTUMNPSR1TSHRRXRA | |
| SCHEMBL11661758 | 0.87 | PPARA (0.60) | PPARANPSR1TSHRRXRARXRB | |
| SCHEMBL9548278 | 0.83 | PPARA (0.52) | PPARANOTUMNPSR1TSHRRXRA | |
| SCHEMBL9849445 | 0.81 | PPARA (0.51) | PPARANPSR1TSHRRXRARXRB | |
| SCHEMBL9548245 | 0.81 | PPARA (0.41) | PPARANOTUMHDAC6HDAC3HDAC1 | |
| SCHEMBL15581446 | 0.80 | NOTUM (0.44) | PPARANOTUMKDM4ELMNAHPGD | |
| Ammonia Solution, Strong SCHEMBL9548251 | 0.80 | PPARA (0.50) | PPARANPSR1TSHRRXRARXRB | |
| SCHEMBL9849579 | 0.79 | PPARA (0.52) | PPARANPSR1TSHRRXRARXRB | |
| SCHEMBL9548297 | 0.79 | PPARA (0.52) | PPARANPSR1TSHRMMP2MMP8 | |
| Iodide SCHEMBL9548248 | 0.78 | PPARA (0.51) | PPARANPSR1TSHRRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1055537-A | 3, two replacement-2-different azoles alkane of 5-and different azoles, its preparation method contain the preparation and the application thereof of this composition | HOECHST AG (DE) | 1991-10-23 | — | — | CN | claimed |
| CN-1055537-A | 3, two replacement-2-different azoles alkane of 5-and different azoles, its preparation method contain the preparation and the application thereof of this composition | HOECHST AG (DE) | 1991-10-23 | — | — | CN | disclosed |