Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9548251 | 0.98 | PPARA (0.50) | PPARASMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9548373 | 0.90 | SMN1; SMN2 (0.46) | PPARASMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL11661758 | 0.86 | PPARA (0.60) | PPARASMN1; SMN2NPC1RAB9AEPHX2 | |
| SCHEMBL9548264 | 0.84 | PPARA (0.50) | PPARASMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9849248 | 0.83 | PPARA (0.54) | PPARASMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9548246 | 0.82 | PPARA (0.45) | PPARASMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9548278 | 0.81 | PPARA (0.52) | PPARASMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL27348673 | 0.81 | PPARA (0.52) | PPARASMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9548297 | 0.78 | PPARA (0.52) | PPARASMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9849579 | 0.78 | PPARA (0.52) | PPARASMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451790-A1 | 3,5-disubstituted 2-isoxazolines and isoxazoles, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-16 | — | — | EP | disclosed |